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human tsp1  (R&D Systems)


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    Structured Review

    R&D Systems human tsp1
    Human Tsp1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 120 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human tsp1/product/R&D Systems
    Average 94 stars, based on 120 article reviews
    human tsp1 - by Bioz Stars, 2026-03
    94/100 stars

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    anti tsp1  (R&D Systems)
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    (A) Representative H&E staining and tissue compartment analysis with the top 20 enriched genes in each compartment. THBS1 was highlighted by red rectangles. Red arrow indicates dissection sites (presence of red blood cells). “L” indicates the aortic lumen. (B) Expression and distribution of COL1A1 , COL3A1 , TAGLN , and THBS1 in representative AAA tissue. (C) Immunostaining of human AAA cross-sections with anti-MYH11 and <t>anti-TSP1.</t> The yellow dashed ellipse indicates the dissection site. (D) TGFβ (TGFB) pathway activity and expression of ligands and receptors of TGFβ signaling in AAA tissue.
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    (A) Representative H&E staining and tissue compartment analysis with the top 20 enriched genes in each compartment. THBS1 was highlighted by red rectangles. Red arrow indicates dissection sites (presence of red blood cells). “L” indicates the aortic lumen. (B) Expression and distribution of COL1A1 , COL3A1 , TAGLN , and THBS1 in representative AAA tissue. (C) Immunostaining of human AAA cross-sections with anti-MYH11 and anti-TSP1. The yellow dashed ellipse indicates the dissection site. (D) TGFβ (TGFB) pathway activity and expression of ligands and receptors of TGFβ signaling in AAA tissue.

    Journal: bioRxiv

    Article Title: Myeloid-Specific Thrombospondin-1 Deficiency Exacerbates Aortic Rupture via Broad Suppression of Extracellular Matrix Proteins

    doi: 10.1101/2024.07.30.605216

    Figure Lengend Snippet: (A) Representative H&E staining and tissue compartment analysis with the top 20 enriched genes in each compartment. THBS1 was highlighted by red rectangles. Red arrow indicates dissection sites (presence of red blood cells). “L” indicates the aortic lumen. (B) Expression and distribution of COL1A1 , COL3A1 , TAGLN , and THBS1 in representative AAA tissue. (C) Immunostaining of human AAA cross-sections with anti-MYH11 and anti-TSP1. The yellow dashed ellipse indicates the dissection site. (D) TGFβ (TGFB) pathway activity and expression of ligands and receptors of TGFβ signaling in AAA tissue.

    Article Snippet: PFA-fixed tissue sections were blocked with normal donkey serum (10% vol/vol) and incubated at 4 °C overnight with primary antibodies anti-F4/80 (123102, BioLegend), anti-Col1a1 (NB600-408, Novus Biologicals), anti-MYH11 (ab53219, abcam), anti-TSP1 (AF3074, R&D Systems).

    Techniques: Staining, Dissection, Expressing, Immunostaining, Activity Assay